When Can I Take Ibuprofen After Finishing Prednisone - T-Tees - Your Answers Await, Life's Questions Unraveled

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It’s important to tell your doctor or pharmacist what medicines you’re already taking, including those bought without a prescription and herbal medicines, before you start taking prednisolone. Similarly, check with your doctor or pharmacist before taking any new medicines with prednisolone, to make sure that the combination is safe.

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Can I take over-the-counter medicines with prednisolone?

If you’re taking gastro-resistant prednisolone tablets, don’t take antacids (indigestion remedies) at the same time of day. Avoid taking antacids within two hours of taking this type of prednisolone tablet.

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Don’t take anti-inflammatory painkillers (NSAIDs) like aspirin, ibuprofen or naproxen while you’re taking prednisolone, unless they’ve been prescribed by your doctor. This type of painkiller may increase the risk of side effects on the gut, such as stomach ulceration and bleeding.

Remember that many cold and flu remedies and over-the-counter painkillers contain ibuprofen or aspirin and so should be avoided while you’re taking prednisolone. Be sure to check the ingredients of other medicines before taking them with prednisolone, or ask your pharmacist for advice.

It’s fine to take paracetamol with prednisolone. You can also take opioid-type painkillers such as codeine or co-codamol.

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Check with your doctor or pharmacist before using steroid creams (eg for eczema or allergic skin reactions) or steroid nasal sprays (eg for hayfever) while you’re using prednisolone.

Can prednisolone affect my current medicines?

Prednisolone can cause fluid and salt retention and so may oppose the effects of the following medicines:

antihypertensive medicines used to treat high blood pressure
diuretics, eg furosemide.

Prednisolone may increase blood sugar levels and so may oppose the blood sugar lowering effects of antidiabetic medicines. People with diabetes may need an increase in their dose of insulin or antidiabetic tablets.

Prednisolone may enhance the anti-blood-clotting effect of anticoagulant medicines such as warfarin. If you’re taking warfarin with prednisolone your blood clotting time (INR) should be regularly monitored, particularly after starting or stopping treatment with prednisolone and after any dose changes.

The level of potassium in your blood is more likely to fall too low if you take prednisolone with other medicines that can lower the amount of potassium in your blood, such as:

acetazolamide
aminophylline
amphotericin
beta agonists, eg salbutamol, salmeterol, terbutaline
carbenoxolone
liquorice (in large quantities)
potassium-losing diuretics, eg furosemide, bendroflumethiazide
theophylline.

Can I have vaccines while taking prednisolone?

Prednisolone may weaken your immune system, which means that vaccines may be less effective if given during treatment, because your body won’t produce sufficient antibodies in response to the vaccine.

Live vaccines shouldn’t be given to people taking prednisolone because they may cause serious infections. Live vaccines include: measles, mumps, rubella (MMR), BCG, chickenpox, oral typhoid, yellow fever and the nasal spray flu vaccine for children. You shouldn’t be given a live vaccine until at least three months after finishing your course of prednisolone.